What enzyme level is primarily tested to diagnose pancreatitis?

The primary enzyme level tested to diagnose pancreatitis is lipase. Elevated levels of lipase in the blood are a key indicator of acute pancreatitis. This enzyme is produced by the pancreas and plays a crucial role in the digestion of fats. During episodes of pancreatitis, the pancreas becomes inflamed, leading to a release of lipase into the bloodstream, which can be detected through laboratory testing.

While amylase is another enzyme that can be associated with pancreatitis, it is less specific and can be elevated in other conditions such as salivary gland issues or gastrointestinal disorders. Trypsin, although involved in protein digestion and indicative of pancreatic function, is not typically monitored in routine clinical practice for diagnosing pancreatitis. Glucose levels may provide information about pancreatic function over time, especially in cases of chronic pancreatitis due to potential impacts on insulin production, but they are not a direct indicator of acute inflammation of the pancreas. Therefore, lipase stands out as the most relevant and specific enzyme for diagnosing pancreatitis.